Generation of Spherical Microparticles of Moringa Leaves through a Supercritical Antisolvent Extraction Process

The objective of this work was evaluation the supercritical antisolvent extraction (SAE) process to generate microparticles with antioxidant activity from Moringa leaves. A biodegradable polymer used as an inductor particle precipitation. An ethanolic extract 25 mg/mL in SAE process, during which influences pressure (100–200 bar), temperature (35–55 °C) and extract–polymer ratio (0.11–0.33) on size were evaluated. flow rate 3 mL/min, a CO2 (scCO2) 30 g CO2/min nozzle diameter 100 µm kept constant. identification several compounds leaves, namely, coumaric acid quercetin 3D glucoside, determined ultra-performance liquid chromatography coupled mass spectrometry. precipitates measured 2,2-Diphenyl-1-picrylhydrazyl. Spherical diameters range 2–5 obtained, moderate activity.